Transversus Abdominis Plane Block and Postoperative Pain After Laparoscopic Cholecystectomy

Not Applicable

• Conditions: Laparoscopic Cholecystectomy; Abdominal Muscles; Postoperative Pain; Nerve Block
• Interventions: Procedure: Placebo Ultrasound guided subcostal TAP block; Procedure: Ultrasound guided subcostal TAP block

• Registration Number: NCT01595165
• Lead Sponsor: Soonchunhyang University Hospital

Brief Summary

Transversus abdominis plane (TAP) block has gained popularity for the control of postoperative pain in various surgeries. Three studies showed inconsistent result on pain control after TAP block in laparoscopic cholecystectomy. The TAP technique used in these studies was classic ultrasound guided TAP block. Besides periumbilical incision, sub-xiphoid incision is usually made during laparoscopic cholecystectomy. As typical posterior TAP rarely extend above T8, the investigators undergo subcostal TAP block for this type of surgery. The investigators are going to investigate the effect of subcostal TAP on early postoperative pain after laparoscopic cholecystectomy.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-05-07
• Study First Submitted QC: 2012-05-08
• Study First Posted: 2012-05-09
• Status Verified: 2012-07
• Study Start: 2012-07
• Last Update Submitted: 2012-07-05
• Last Update Posted: 2012-07-09
• Primary Completion: 2012-12
• Study Completion: 2013-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• ASA I-II
• Age 20-65 patients scheduled elective laparoscopic cholecystectomy

Exclusion Criteria

• Patient refusal
• Allergy to ropivacaine
• Coagulopathy
• Morbid obesity (BMI>35 kg/m2)
• Previous abdominal surgery.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	Placebo Ultrasound guided subcostal TAP block	Control group receiving saline instead of ropivacaine
TAP	Ultrasound guided subcostal TAP block	TAP group receiving ropivacaine total of 150 mg at TAP under US

Primary Outcome Measures

Name	Time	Method
Numerical Rating Scale (NRS) 15 min after entering recovery room	15 min after entering recovery room

Secondary Outcome Measures

Name	Time	Method
Fentanyl consumption at recovery room	Up to 3 hours until discharge from recovery room
Recovery room stay	Up to 3 hours from entering recovery room to discharge
Incidence of postoperative nausea and vomiting (PONV)	Up to 3 hours during recovery room stay
NRS at 4h, 24h, and 48 h after surgery	4h, 24h, and 48 h after surgery

Trial Locations

Locations (1)

Sang-Hyun Kim; 🇰🇷 Bucheon, Gyeonggi, Korea, Republic of