Effects of an Home-base Physical Activity Program for Counteracting Sarcopenia in Elderly: a Randomized-controlled Trial.
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 16
- Locations
- 2
- Primary Endpoint
- Lower limb strength
Study Overview
Brief Summary
Sarcopenia is a pathophysiological process associated with aging and some metabolic conditions characterized by progressive muscle tissue loss, which may lead to loss of strangth and performance and increase risk of falls and fractures, physical disability and premature death. Therefore, it is necessary to identify personalized programs of physical activity and supplementation for elderly population in order to improve their physical functions, muscle strengh and body composition.
With the present project we aime to assess the effect of a feasible home-based exercise program coupled with food supplementation to improve muscle strength, muscle volume and muscle physical performance potentially associated with sarcopenia in elderly people.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 60 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Sedentary lifestyle.
- •Cognitively intact.
- •Autonomous walking.
- •Acceptance of informed consent.
Exclusion Criteria
- •Body mass index lower than 18.5 and uppen than 40 kg/m
- •History of cancer.
- •Pacemaker user.
- •History of epileptic episodes.
- •Endocrine-metabolic, neurological, muscular and ortopedic pathologies that affect movement functions.
- •Bone fractures that influence movement functions.
- •Surgical treatments in the prior 6 months.
- •Use of antieptilectics, glucocorticoids, rhGH and testosterone.
- •Hepatic and muscular pathologies
Outcomes
Primary Outcomes
Lower limb strength
Time Frame: Baseline and Week 24
Assessed by chair stand test
Secondary Outcomes
- Body composition(Baseline and Week 24)
- Quantify thigh cross sectional area(Baseline and Week 24)
- Maximum isometric force that a hand can squeeze(Baseline and Week 24)
- Maximal Isometric Strength of Knee flexors and extensors(Baseline AND Week 24)
- Dynamic balance and gait deficits(Baseline and Week 24)