Effect of Different Hydration Strategies on Autonomic Acceleration During Recovery in Individuals With Coronary Artery Disease Undergoing Aerobic Exercise
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 31
- 试验地点
- 2
- 主要终点
- Heart rate variability
研究概览
简要总结
The need to restore water losses resulting from physical activity has become established and diffused into international consensus for healthy individuals or high-performance athletes. However, the influence of fluid replacement when administered during and after exercise on cardiac autonomic modulation with autonomic alterations known as the coronary arteries remain poorly understood. The aim of the study was to evaluate and compare whether different hydration strategies are able to promote acceleration of the recovery of autonomic modulation in individuals with coronary artery disease undergoing aerobic exercise. This study is a cross-over clinical trial, which will be developed based on an experimental procedure performed in four stages. A total of 31 individuals will be recruited in this study and will perform four standardized cardiovascular rehabilitation (CR) sessions. The participants will perform CR with mineral water intake in phase three and four. In phase three, the consumption will be done a quantity of water predetermined by the evaluator, based on the loss of body mass measured in the second session. In phase four, hydration will be carried out in an uncontrolled manner, according to the desire to drink water during the protocol.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 —(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Men with coronary heart disease ischemia, over 45 years
- •At least three months of cardiovascular rehabilitation
排除标准
- •Smokers, alcoholics
- •Uncontrolled metabolic disease (eg, uncontrolled diabetes and thyroid diseases)
- •Abnormal hemodynamic responses during exercise such as disproportionate increase / fall of heart rate and / or blood pressure to low / high levels of load
- •Myocardial ischemia and / or severe ventricular arrhythmias during the exercise test
结局指标
主要结局
Heart rate variability
时间窗: up to six months
Linear indices of heart rate variability in the time domain (SDNN, rMSSD).
次要结局
未报告次要终点
研究者
Luiz Carlos Marques Vanderlei
Principal Investigator
Universidade Estadual Paulista Júlio de Mesquita Filho
