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临床试验/NCT04865614
NCT04865614已完成不适用

Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair

Heidelberg University1 个研究点 分布在 1 个国家目标入组 57 人开始时间: 2019年4月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
57
试验地点
1
主要终点
Post-induction hypotension

研究概览

简要总结

The induction of anaesthesia is one of the most critical situations for high-risk-patients undergoing interventions surgery. For several reasons, it is crucial to maintain adequate blood pressure and cardiac output during this phase.

This retrospective cohort study aims to find out if the choice of the induction agent has a major impact on blood pressure and the use of catecholamines during the induction and the interventional procedure in patients undergoing interventional mitral valve repair.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients undergoing elective interventional mitral valve repair
  • Sevoflurane or etomidate have been used for induction of anesthesia

排除标准

  • Pregnancy

研究组 & 干预措施

Etomidate group

Patients who received etomidate for induction of anaesthesia during interventional mitral valve repair (Mitraclip)

干预措施: Etomidate (Drug)

Sevoflurane group

Patients who received sevoflurane for induction of anaesthesia during interventional mitral valve repair (Mitraclip)

干预措施: Sevoflurane (Drug)

结局指标

主要结局

Post-induction hypotension

时间窗: First 20 minutes after induction of anaesthesia

Hypotension in the first 20 minutes after induction of anesthesia

次要结局

  • Use of catecholamines(Length of procedure (Approximately 60 to 90 minutes in average))
  • Use of catecholamines after induction during the first 20 minutes after inductionafter induction(First 20 minutes after induction)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr. Adrian Stephan

Principal Investigator

Heidelberg University

研究点 (1)

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