Effect of Acute Decompensation(complication of liver disease) in Patients with liver disease

Not Applicable

• Conditions: Health Condition 1: null- Acute Decompensation in CirrhosisHealth Condition 2: K746- Other and unspecified cirrhosis ofliver

• Registration Number: CTRI/2018/03/012321
• Lead Sponsor: Institute of liver and Biliary Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Other (Terminated)
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.Cirrhosis with decompensation in a period of 3 months in form of ascites, jaundice, HepaticEncephalopathy, Acute Variceal bleed irrespective of prior decompensation.

2.Age 18-70 years

3.Valid consent

Exclusion Criteria

1.HepatoCellular Carcinoma

2.Admitted and survival less than 48 hrs

3.Pregnant

4.Acute Liver Failure

5.Post Transplant

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Spontaneous recovery, liver transplant or death in 90 daysTimepoint: 90 days

Secondary Outcome Measures

Name	Time	Method
Cause of acute decompensation.Timepoint: 90 days;Causes of deathTimepoint: 90 days;Improvement in severity assessment Indices (MELD, CTP, SOFA, APACHE II and CLIF SOFA scores)Timepoint: 90 days;Profile of patient undergone transplantTimepoint: 90 days;Sepsis, SIRS and infectionTimepoint: 90 days;Severity and duration of prior as well as present decompensationTimepoint: 90 days