Influence of Periodontal Diseases on Vascular Parameters in Patients Suffering of Hypertension

Terminated

• Conditions: Chronic Periodontitis; Hypertension
• Interventions: Other: echo Doppler lower limbs

• Registration Number: NCT02394860
• Lead Sponsor: University Hospital, Strasbourg, France

Brief Summary

The aim of this study is to assess the influence of the severity of chronic periodontitis on hemodynamic parameters in hypertensive patients.Secondary purposes of this protocol is to identify evolution of several biomarkers and correlate the clinical situation with oral microflora.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-07-08
• Study First Submitted QC: 2015-03-16
• Study First Posted: 2015-03-20
• Study Start: 2015-04
• Primary Completion: 2024-02
• Study Completion: 2024-02
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-16
• Last Update Posted: 2024-08-19

Recruitment & Eligibility

• Status: TERMINATED
• Sex: Male
• Target Recruitment: 76

Inclusion Criteria

• -Men- >40 years
• moderate and severe generalized chronic periodontitis
• Former diagnosis of hypertension
• >12 teeth

Exclusion Criteria

• >70 years
• smokers (>10 cig/day)
• body mass index>30
• Need of antibioprophylaxis
• Medical treatment including anti-inflammatory drugs and/or antibiotics
• Refractory form of hypertension- aggressive periodontitis

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
blood and cardiological examination	echo Doppler lower limbs	-

Primary Outcome Measures

Name	Time	Method
Measuring the thickness of the intima-media	15 days

Secondary Outcome Measures

Name	Time	Method
Evaluation of anatomical changes that may occur at the arterial level	Within 15 days after inclusion

Trial Locations

Locations (1)

Service de parodontologie; 🇫🇷 Strasbourg, France