ISRCTN61380683已完成不适用

Single high dose of inhaled steroid on exercise induced laryngeal narrowing and bronchial asthma in children: a double-blind randomised cross-over placebo controlled trial

Paediatric Research Foundation Enschede, Medical Centre Twente (Netherlands)0 个研究点目标入组 23 人开始时间: 2009年12月8日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Clinical history of airway obstruction after exercise
•2. A drop of FEV1 of at least 10% after exercise
•3. Aged between 12 and 17 years, either sex
•4. Ability to perform reproducible lung function tests, i.e., coefficient of the predicted value variation in three of five consecutive measurements less than 5%
•5. FEV1 greater than 70% of predicted value
•6. Clinically stable period of at least 3 weeks before the study period

•1. Use of inhaled, intranasal or systemic corticosteroids in the last 4 weeks prior to the study
•2. Use of anti-histamines, leucotrienes receptor antagonists, cromoglycates, anticholinergics and long acting bronchodilators in two weeks prior to the study
•3. Other pulmonary or cardiac disorder
•4. Deviation of more than 12% from baseline spirometry at a subsequent exercise challenge

发起方

Paediatric Research Foundation Enschede, Medical Centre Twente (Netherlands)