Association Between Peri-procedural Myocardial Injury and Quantitative Blood Flow Ratio

Completed

• Conditions: Coronary Arterial Disease (CAD)

• Registration Number: NCT07110298
• Lead Sponsor: The First Affiliated Hospital of Xiamen University

Brief Summary

to apply angiography-based quantitative blood flow ratio to quantify the severity of the stenosed coronary artery prior to percutaneous coronary intervention, and monitor per-procedural myocardial injury based on the troponin level.Finally, to find the relationship between quantitative blood flow ratio results and myocardial injury degree.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-01
• Primary Completion: 2023-05-31
• Study Completion: 2023-05-31
• Status Verified: 2025-07
• Study First Submitted: 2025-07-31
• Study First Submitted QC: 2025-07-31
• Last Update Submitted: 2025-07-31
• Study First Posted: 2025-08-07
• Last Update Posted: 2025-08-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• unstable angina patients

Exclusion Criteria

• (1) multivessel diseases needed to be bypassed; (2) no track of high-sensitivity troponin I (hs-CTNI) level after PCI; (3) the elevated hs-CTNI level before PCI; (4) patients refusal to PCI; (5) side branch occlusion after PCI; (6) PCI failure with the main vessels occlusion; (7) eGRF (estimated glomerular filtration rate) less than 30ml/min/1.73m2; (8) no acquisition of QFR results because of the non-ideal angiographic quality.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cardiovascular adverse events	three months
Major cardiac adverse events	three months follow-up

Trial Locations

Locations (1)

the First Affiliated Hospital of Xiamen University; 🇨🇳 Xiamen, Fujian, China