Validation of a Hand-Held Dynamometer for Assessment of Lower Limb Muscle Strength in Multiple Sclerosis: Protocol for Strength Testing and Reliability Characteristics
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Brown, Theodore R., M.D., MPH
- Enrollment
- 21
- Locations
- 1
- Primary Endpoint
- Assessment of HHD
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
Evaluate a method of testing the strength of five key lower limb muscle groups using a hand-held strength gauge (dynamometer).
Detailed Description
Purpose of this study is to assess the intra-rater and inter-rater reliability of a hand-held dynamometer (HHD) in the assessment of lower limb strength in patients with Multiple Sclerosis. Also to establish a standardized strength testing procedure for key lower limb muscle groups using a HHD fo research and clinical purposes in Multiple Sclerosis.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Stable patients with clinically definite Multiple Sclerosis
- •No Multiple Sclerosis exacerbation 30 days prior to screening
- •No change in disease modifying therapy for 30 day prior to screening
Exclusion Criteria
- •Inflammatory myopathy
- •Endocarditis, pericarditis o rother unstable heart disease
- •Cardiac surgery or myocardial infarction in the last 3 months
- •Decompensated congestive heart failure
- •Severe aortic stenosis
- •Severe pulmonary hypertension
- •Pulmonary embolus or infarction in the last 6 months
- •Uncontrolled hypertension by history or by screening or baseline diastolic blood pressure \>170 or systolic blood pressure \>105
- •Concomitant neurodegenerative neurological disease such as Amyotrophic Lateral Sclerosis (ALS) Parkinsons or hemiplegic stroke
- •females who are pregnant
Outcomes
Primary Outcomes
Assessment of HHD
Time Frame: Outcome measures will be assessed once we have captured all data points for all 21 subjects.
To assess the intra-rater and inter-rater reliability of a hand-held dynamometer(HHD) in the assessment of lower limb strength in patients with Multiple Sclerosis. To establish a standardized strength testing procedure for key lower limb muscle groups using a HHD for research and clinical purposes in Multiple Sclerosis.
Secondary Outcomes
- Validation of a Hand-held dynamometer for assessment of lower limb muscle strength.(outcome measures will be assessed once we have captured all data points for all 21 subjects)