跳至主要内容
临床试验/CTRI/2024/12/078172
CTRI/2024/12/078172进行中(未招募)不适用

An Observational Study to evaluate the role of Rasadhatu Dushti in Lifestyle disorders wsr to PCOD

Shri Narayan Prasad Awasthi Government Ayurved College1 个研究点 分布在 1 个国家目标入组 110 人开始时间: 2025年1月1日最近更新:

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
110
试验地点
1
主要终点
Significant role played by Rasa dhatu dushti in the manifestation of PCOD will be established

研究概览

简要总结

Ayurveda is a holistic science which primarily aims at maintaining health of a person1 .Ayurveda

have stated many principles including dincharya (rules regarding daily routine), ritucharya (rules to be

followed in every season), sadavritta (rules regarding basic ethics), all these, concludes a good healthy

life.

Day by day this practice has been deteriorating. Excessive sugary intake, lack of exercise and

physical activities, sedentary lifestyle leads to the disturbance of normal circadian rhythm and hence

making it an impactful cause of many diseases. These group of diseases are termed as lifestyle disorders.

One such common disease affecting females is PCOD (polycystic ovarian disease), availing

about 8-13% of total reproductive female age group population as stated by WHO. It is characterised

by irregular menstrual cycles, oligomenorrhea or hypomenorrhea, hirsutism, weight gain, infertility,

hair fall, acanthosis and other symptoms of androgen excess. Obesity leads to Insulin resistance and LH

resistance in the body which further dismiss rupture of graffian follicle and hence immature follicles

rise in ovary which enhance the release of excessive estrogen. This excessive estrogen is then converted

into androgens in peripheral fat cells thus concluding the androgenic picture of PCOD.

In Ayurveda PCOD can be categorised under Artava vaha strotas vikar. Artava or Raja is

mentioned as the upadatu of Rasa Dhatu. Rasa dhatu is the foremost dhatu formed from aahaar rasa

and contain all the nutrients which are required for the development of remaining dhatus of the body.

Over a period of one month, Rasa gets matured and processed, this is then converted into shukra in men

and artava (menstrual blood, ovum) in females.Consequently, it takes a full month for the proper

development of artava during the monthly menstrual cycle.

PCOD (polycystic ovarian disease) has been a global issue and exhibit symptoms of disturbed menstrual cycle. Ayurveda implies rasa dhatu as the important factor governing ritucharya or menstrual cycle.

So, based upon current scenario, this study focuses upon governing one of the important factor

that is Rasa dhatu, factors responsible for its vitiation and its effect in terms of PCOD

PCOD (polycystic ovarian disease) has become the common disorder among the females of

reproductive age group contributing about 8-13%. In India it accounts for 10% of total reproductive age

group females4

. Its most common adverse effect on the society is infertility leading to population

imbalance and hence affecting working man power. There is no etiology assessed for this disease till

now. It has been stated as the hormonal disorder but there is no such evidence stating the reason behind

these disturbed hormonal levels.

Hence, there is a fair chance to study the etiology of PCOD by assessing the important factor,

Rasa dhatu, as artaav is the upadhatu of rasa dhatu and it has to be dependent on the status of rasa

dhatu. Hence, if we find out any link between the occurrence of PCOD with Rasa dhatu dushti then we

can try to manage PCOD by means of Rasa dhatu dushti correction with the help of Aahaar, Vihaar,

bheshaj and nidanparivarjana.

The main of this study is the prevention of the disease. Nidanaparivarjan plays the key role and

hence establishment of this link will commence the utmost need to adapt the basic principles of

Ayurveda regarding diet(aahaar), daily routine, rules to be adopted during menstrual cycle (rajaswala

paricharya) especially during puberty period.

Hence, there is a need to evaluate the link between the disease (PCOD) and Rasa dhatu dushti.

Also, this study can act as the basic research for further study regarding the management of disease, its

better prognosis and ultimately prevention of the disease.

Keeping all these in mind, the need for present research work is felt.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 40.00 Year(s)(—)
性别
Female

入选标准

  • Diagnosed Patients of PCOD
  • Female Patients of age group 18-40 years
  • Selection of Patients irrespective of religion, socioeconomic status and marital status
  • Patient who are willing to participate in the study and agrees to sign consent form.

排除标准

  • Female with menopausal syndrome
  • Pregnant and Lactating mothers
  • Patients with other functional and structural pathology of reproductive system like fibroid carcinoma polyp and other new growth (benign/malignant) or patient having malignancies in any system.
  • Patient with congenital anomalies of reproductive system.
  • Patient suffering from endocrinal disorders.
  • Patient suffering from severe systemic infections and tuberculosis.
  • Patient who are not willing to participate in the study and does not agree to sign consent form.

结局指标

主要结局

Significant role played by Rasa dhatu dushti in the manifestation of PCOD will be established

时间窗: 1 year

There will be strong association between Rasa dhatu dushti and PCOD on assessment scale.

时间窗: 1 year

次要结局

  • There will be strong association between Rasa dhatu dushti and PCOD on assessment scale.(1 year)

研究者

发起方
Shri Narayan Prasad Awasthi Government Ayurved College
申办方类型
Other [Government Ayurved College ]
责任方
Principal Investigator
主要研究者

Pratiksha Paitod

Shri Narayan Prasad Awasthi Government Ayurved College Raipur Chhattisgarh 492010

研究点 (1)

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