Vitamin D and Serum Calcium Level Insufficiency and Early Dental Implant Failure
- Conditions
- Dental Implant Failure NosVitamin D Deficiency
- Interventions
- Diagnostic Test: Vitamin D and calcium levels
- Registration Number
- NCT04906161
- Lead Sponsor
- Ain Shams University
- Brief Summary
In this study there is a trial to investigate whether there is a correlation between early implant failure and low serum levels of vitamin D.
- Detailed Description
Osseointegration is a complex phenomenon and depends on many factors; some are related to the implant (material, macroscopic design, and implant surface), others to the surgical-prosthetic protocol (surgical technique, loading conditions, and time), and others to the patient (quantity/quality of bone at the receiving site and the host response)
All these observations would suggest the existence of specific patient-related risk factors such as vitamin D deficiency in the blood, could play an important role in the occurrence of early dental implant failures (EDIFs), but unfortunately are neglected by the dental literature.
In this study there is a trial to investigate whether there is a correlation between early implant failure and low serum levels of vitamin D. Therefore we are including patients with early implant failure during the year 2020 using the same implant (material, macroscopic design, and implant surface), surgical-prosthetic protocol (surgical technique, loading conditions, and time)
The study will be performed into 15 male and 15 female participants that had dental implant placement in the last 3 months. An informed consent will be signed with the patient with full detail on the study.
The situation of the implant will be categorized into either successful or failed dental implant.
Medical history and lifestyle information will be obtained by questionnaire. Levels of serum vitamin D will be collected from participants
Statistical analysis will correlate between vitamin D and early implant failure.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 30
- Missing single tooth
- Systemically free
- Average body mass index
- Systemic conditions
- Bad oral hygiene
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Successful dental implant Vitamin D and calcium levels Patients showed a successful implant placement with no complications before loading Early dental implant failure Vitamin D and calcium levels Early complications and failure of dental implant before loading
- Primary Outcome Measures
Name Time Method Implant success with normal serum vitamin D level 6 months Implant stability with no further radiographic bone loss following bone remodeling with successful prosthetic part
Early implant failure with deficient serum vitamin D level 6 months Mobile extruded implant with radiographic bone loss and peri-implant pathosis
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Doaa Khattab
🇪🇬Cairo, Abbassia, Egypt
Ain Shams University
🇪🇬Cairo, Abbassia, Egypt