MedPath

Vitamin D and Serum Calcium Level Insufficiency and Early Dental Implant Failure

Conditions
Dental Implant Failure Nos
Vitamin D Deficiency
Interventions
Diagnostic Test: Vitamin D and calcium levels
Registration Number
NCT04906161
Lead Sponsor
Ain Shams University
Brief Summary

In this study there is a trial to investigate whether there is a correlation between early implant failure and low serum levels of vitamin D.

Detailed Description

Osseointegration is a complex phenomenon and depends on many factors; some are related to the implant (material, macroscopic design, and implant surface), others to the surgical-prosthetic protocol (surgical technique, loading conditions, and time), and others to the patient (quantity/quality of bone at the receiving site and the host response)

All these observations would suggest the existence of specific patient-related risk factors such as vitamin D deficiency in the blood, could play an important role in the occurrence of early dental implant failures (EDIFs), but unfortunately are neglected by the dental literature.

In this study there is a trial to investigate whether there is a correlation between early implant failure and low serum levels of vitamin D. Therefore we are including patients with early implant failure during the year 2020 using the same implant (material, macroscopic design, and implant surface), surgical-prosthetic protocol (surgical technique, loading conditions, and time)

The study will be performed into 15 male and 15 female participants that had dental implant placement in the last 3 months. An informed consent will be signed with the patient with full detail on the study.

The situation of the implant will be categorized into either successful or failed dental implant.

Medical history and lifestyle information will be obtained by questionnaire. Levels of serum vitamin D will be collected from participants

Statistical analysis will correlate between vitamin D and early implant failure.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Missing single tooth
  • Systemically free
  • Average body mass index
Read More
Exclusion Criteria
  • Systemic conditions
  • Bad oral hygiene
Read More

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Successful dental implantVitamin D and calcium levelsPatients showed a successful implant placement with no complications before loading
Early dental implant failureVitamin D and calcium levelsEarly complications and failure of dental implant before loading
Primary Outcome Measures
NameTimeMethod
Implant success with normal serum vitamin D level6 months

Implant stability with no further radiographic bone loss following bone remodeling with successful prosthetic part

Early implant failure with deficient serum vitamin D level6 months

Mobile extruded implant with radiographic bone loss and peri-implant pathosis

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Doaa Khattab

🇪🇬

Cairo, Abbassia, Egypt

Ain Shams University

🇪🇬

Cairo, Abbassia, Egypt

© Copyright 2025. All Rights Reserved by MedPath