Assessment of Hydration Status Using Bioelectrical Impedance Vector Analysis in Critical Patients With Acute Kidney Injury
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Kidney Injury
- Sponsor
- Catholic University of Pelotas
- Enrollment
- 224
- Primary Endpoint
- Proportion of survivors in patients with AKI diagnosis during ICU
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The state of hyperhydration in critically ill patients with acute kidney injury (AKI) is associated with increased mortality. Bioelectrical impedance vector analysis (BIVA) appears to be a viable method to access the fluid status of critical patients but has never been evaluated in critical patients with AKI. The objective of this study is to evaluate the hydration status using BIVA in critical patients under intensive care at the time of AKI diagnosis and to correlate this measurement with mortality. A sample of 224 patients with AKI will be evaluated by BIVA and followed until they are discharged or death in intensive care unit and the BIVA vectors will be analysed to define differences in hydration characteristics from each group.
Detailed Description
Patients admitted to Intensive Care Unit (ICU) will be assessed by BIVA at the moment of the AKI diagnosis. They will be followed up to 12 weeks, until hospital discharge or death. The association between survival and hydration status, as assessed by BIVA in the first AKI day, will be tested.
Investigators
Maria Cristina Gonzalez
Full Professor
Catholic University of Pelotas
Eligibility Criteria
Inclusion Criteria
- •Patients older than 18 years who developed acute kidney injury after admission in Intensive Care Unit
Exclusion Criteria
- •Chronic kidney injury, dialysis-dependent chronic kidney injury, acute kidney injury before ICU admission, kidney transplant, morbidity obesity and limb amputation.
Outcomes
Primary Outcomes
Proportion of survivors in patients with AKI diagnosis during ICU
Time Frame: Up to 12 weeks after AKI diagnosis
Patients admitted in ICU will be followed up to 2 weeks after AKI diagnosis and survival will be analyzed according to their hydration status assessed by BIVA.