MedPath

Effect of Adrenaline Concentration on Intraoperative Hemodynamics of Liposuction Patients

Phase 3
Completed
Conditions
Intraoperative Hemodynamics
Liposuction
Registration Number
NCT05822765
Lead Sponsor
Al-Azhar University
Brief Summary

Liposuction is a procedure that has emerged over the last 30 years as a method to remove subcutaneous fat for cosmetic purposes. Numerous liposuction techniques have been developed .Tumescent liposuction involves using large volumes of dilute local anesthetic and epinephrine to facilitate anesthesia and decrease blood loss. Questions remain about the appropriate dose of local anesthetic, the use of general anesthesia in liposuction, and the setting in which the chosen liposuction method is used. Adrenaline is the most commonly used vasoconstrictor, the recommended concentration in the tumescent solution is 0.25-1 mg/L depending on the tissue vascularity. In the more vascular tissues, the concentration is 1 mg/L and is decreased to 0.5 mg/L in the less vascular areas of the body. The dose should not exceed 50μg/kg. If the maximum dose is anticipated to exceed, the procedure should be done in several stages.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40
Inclusion Criteria
  • ASA I patients
  • scheduled for liposuction for abdomen and flanks and body contouring with liposuction
Exclusion Criteria
  • Bleeding disorders, anemia or hemoglobin level less than 11g/dl
  • Cardiovascular diseases,
  • Uncontrolled diabetes mellitus,
  • Collagen disorders, and
  • Pregnancy

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Blood pressure4 hours

Noninvasive Blood pressure will be recorded

Secondary Outcome Measures
NameTimeMethod
Heart rate4 hours

Heart rate will be recorded every 10 minutes and results will be recorded

Trial Locations

Locations (1)

Neveen Kohaf

🇪🇬

Tanta, Egypt

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