NL-OMON54044已完成4 期
Spinal morphine in patients with hip fractures to reduce delirium - SALMON-mind
Maasstadziekenhuis0 个研究点目标入组 200 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 200
研究概览
简要总结
Trial ended prematurely
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Proximal femur fracture
- •Scheduled for surgerical treatment
- •Spinal anesthesia
排除标准
- •Contraindications for spinal anesthesia:
- •- Coagulation disorders (clopidogrel, INR>1.8, anticoagulation with nadroparine
- •(>100 aXa-IE/kg) or heparine (APTT> 30 sec), recent use of a Direct Oral
- •Anticoagulant, as stated in the guideline *Neuraxisblokkade en antistolling* by
- •the Dutch Society of Anesthesiology.
- •- Aortic Valve Stenosis of AVA < 1.0 cm2
- •- Lumbar malformations (local inflammation, lumbar osteosynthesis material,
- •meningocele, tethered cord)
- •- Inability to retrieve cerebrospinal fluid by lumbar puncture.
- •Contra-indications for intrathecal morphine:
- •- Chronic opioid or benzodiazepine use (>1 month daily use).
- •- Allergies to amide-type local anesthetics and morphine.
- •- Patients* refusal
- •- Patients who are incapable of making decisions regarding anesthesia and no
- •legal representative is available.
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