Effect of Core Stabilization exercises and Lumbar mobilization on pain,IL-6 and muscle activity in Lumbar Spondylosis.
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- Numeric Pain Rating Scale
研究概览
简要总结
Effect of Core Stabilization Exercises and Lumbar Mobilization on Pain, IL-6 and Muscle activity in Lumbar Spondylosis
Lumbar Spondylosis (LS) is a degenerative condition of lumbar spine affecting intervertebral disc and vertebral bodies.With advancing age, degenerated disc released proinflammatory mediators like IL6 which initiate the inflammation resulting into pain and alter muscles activity as well as recruitment pattern of deep core muscles like Transverse Abdominis and Lumbar multifidus, which might affect stability of spine.Apart from this, Interleukin-6 also induces bone resorption and degeneration which reduces lumbar mobility.
Hence, the purpose of this trial is to find out the added effect of core stabilization exercise and lumbar mobilization in Lumbar spondylosis on pain intensity, IL6, muscle activity, lumbar ROM and function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 40.00 Year(s) 至 60.00 Year(s)（—）
入选标准
- •1.Lumbar spondylosis without radiculopathy.
- •(Kellegren Lawrence grading 2 to 3) 2.Age groups—40 to 60 years.
- •3.Gender—male and female.
- •4.History of slow, insidious onset of pain.
- •5.On Physical examination Limited ROMs of lumbar spine like extension, flexion or side flexion.
- •Nature of pain -aching pain.
- •6.Diagnosis confirmed by X-Ray showing signs of degeneration.
排除标准
- •1.Subject with history of Previous spinal surgery & fractures.
- •2.Presence of Spinal deformity-scoliosis, Spinal neoplasm or metastatic disease 3.Progressive neuropathy or progressive lumbosacral radiculopathy, neurological deficits.
- •4.Spondylolysis, Spondylolisthesis & Osteoporosis.
- •5.Known rheumatic, neurologic, or mental diseases.
- •6.Other red flags (contra-indications) to manual therapy and LASER.
结局指标
主要结局
Numeric Pain Rating Scale
时间窗: Baseline and at the end of 4th week
IL6 Blood Test
时间窗: Baseline and at the end of 4th week
Surface EMG
时间窗: Baseline and at the end of 4th week
次要结局
- Bubble Inclinometer.(Oswestry Disability Index.)
研究者
Lilima Patel
PhD Scholar