A Virtually Delivered Memory Rehabilitation Protocol in Older Adults

Not Applicable

Completed

• Conditions: Memory Dysfunction; Neurorehabilitation

• Registration Number: NCT06187857
• Lead Sponsor: Brigham Young University

Brief Summary

The investigators conducted a feasibility study of a virtually-delivered adaptation of an ecologically oriented neurorehabilitation of memory (EON-Mem) in improving memory for healthy older adults. The primary purposes of this study included determining the feasibility of conducting EON-Mem virtually with older adults and whether a randomized control trial using EON-Mem in older adults is of value.

Detailed Description

Twenty-five older adults aged 55 years and older were recruited for participation in the EON-Mem training program adapted and administered virtually. Measures of emotional functioning and cognitive functioning were administered before and following the intervention. Participants attended one virtual treatment session per week for a total of six weeks with daily homework assignments. A priori, feasibility was set at an 80% completion rate. To address questions regarding feasibility, the investigators calculated descriptive statistics on sample information.

Study Timeline

• Study Start: 2020-12-01
• Primary Completion: 2021-12-20
• Study Completion: 2021-12-20
• Study First Submitted: 2023-11-27
• Status Verified: 2023-12
• Study First Submitted QC: 2023-12-28
• Last Update Submitted: 2023-12-28
• Study First Posted: 2024-01-03
• Last Update Posted: 2024-01-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Individuals 55 and older

Exclusion Criteria

• Evidence of cognitive dysfunction on the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) as evidenced by a score of 3.3 or more
• History of moderate-to-severe TBI
• History of stroke
• Dementia/neurological diagnoses
• Current chemotherapy or radiation
• Current or history of brain cancer
• Poor sensory function including uncorrected vision, hearing, or speaking impairments that could interfere with learning the intervention, including nonnative English speakers.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Feasibility of study protocols.	Through study completion, an average of 8 weeks.	To address questions regarding feasibility, the investigators calculated descriptive statistics on sample information and feasibility was set a priori as a completion rate greater than 80% based on previous research.

Secondary Outcome Measures

Name	Time	Method
Memory Outcomes: Ecological Memory Simulations	Through study completion, an average of 8 weeks.	To address secondary outcomes, the investigators calculated reliable change indices for memory outcomes on the Ecological Memory Simulations. The reliable change indices vary from less than -1.96 to greater than 1.96. Greater than 1.96 represents improved memory functioning.
Memory Outcomes: Repeatable Battery for Neuropsychological Status	Through study completion, an average of 8 weeks.	To address secondary outcomes, the investigators calculated reliable change indices for memory outcomes on the Repeatable Battery for Neuropsychological Status. The reliable change indices vary from less than -1.96 to greater than 1.96. Greater than 1.96 represents improved memory functioning.

Trial Locations

Locations (1)

Brigham Young Unversity; 🇺🇸 Provo, Utah, United States