The role of arm swing in gait: a combined EEG-EMG study in healthy participants and PD patients

Completed

Conditions: Parkinson
Parkinson's disease
10028037

Registration Number: NL-OMON46309

Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 45

Inclusion Criteria

Healthy individuals:
o Perceived healthy
o Able to walk independently (without support)
o Age * 18 years and < 80 years, age- and sex-matched with PD patients for case-control study
o Right-handed according to the Annett Handedness scale
o Written informed consent
All PD Patients:
o Able to walk independently (without support) (Hoehn & Yahr scale: Stage 2-3)
o PD diagnosis according to the UK Parkinson*s Disease Society Brain Bank criteria (A.J. Hughes, 1992)
o Trouble initiating gait (as reported in the medical file)
o Age < 80 (to limit the presence of vascular problems)
o Right-handed according to the Annett Handedness scale
o Written informed consent

Exclusion Criteria

All participants
* Mini Mental State Examination (MMSE) score <26 (to exclude low task performance due to cognitive disabilities)
* (other) neurological or motor disorder (for patients: other than PD)
* Use of medication influencing movement (for patients: other than for PD)
PD patients
* Tremor-dominant PD

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Measures of cortico-cortical, cortico-muscular and musculo-muscular coupling<br /><br>(derived from dynamic coherence analysis), compared between the different<br /><br>walking tasks and between PD patients and controls. In addition, measures of<br /><br>gait such as step duration, gait velocity and walking rhythm during the<br /><br>different tasks, compared between different walking tasks and between patients<br /><br>and controls. </p><br>

Secondary Outcome Measures