The effect of ingesting a whey and collagen protein blend on myofibrillar and connective tissue protein synthesis rates at rest and during recovery from exercise
Completed
- Conditions
- Muscle and connective tissue research (no disorders)Connective tissueMuscle health
- Registration Number
- NL-OMON51634
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 38
Inclusion Criteria
- Males
- Aged between 18-35 years
- Healthy, recreationally active (performing exercise between 1 and 4 times per
week in the past 6 months)
- BMI 18.5 - 30 kg/m2
- No physical limitations (i.e. able to perform all activities associated with
daily living in an independent manner).
Exclusion Criteria
- Females
- Musculoskeletal disorders
- Use of any medications known to affect protein metabolism (i.e.
corticosteroids, non-steroidal anti-inflammatories, or prescribed acne
medications).
- Participation in any structured regular exercise program
- Chronic use of gastric acid suppressing medication or anti-coagulants
- Pathologies of the gastrointestinal tract
- Blood donation in the past 2 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>- Myofibrillar protein-bound L-[ring-13C6] phenylalanine enrichment (expressed<br /><br>as MPE)<br /><br>- Muscle connective tissue protein-bound L-[ring-13C6] phenylalanine enrichment<br /><br>(expressed as MPE)<br /><br>- Average plasma L-[ring-13C6] phenylalanine enrichment over the 3.5 h period<br /><br>before the study beverage and 5 h postprandial period.</p><br>
- Secondary Outcome Measures
Name Time Method <p>* Plasma amino acid concentrations (expressed as *mol/L)<br /><br>* Total plasma amino acids (AAmax [*mol/L])<br /><br>* Plasma glucose (glucosemax [mmol/L])<br /><br>* Plasma insulin (insulinmax [mU/L])</p><br>