The Effects of sodium butyrate supplementation on obesity

Phase 2

Recruiting

• Conditions: Obesity.; Obesity due to excess calories; E66.0

• Registration Number: IRCT20190303042905N3
• Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 12 July 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Body mass index (BMI) between 30-40
Both of genders female and male
Age between 18-60 years old

Exclusion Criteria

Unwillingness to participate in the study
Kidney diseases
liver failure
heart failure
rheumatic diseases
diabetes
malignancies, and gastrointestinal diseases
Taking weightloss drugs and following a weight loss diet
History of bariatric surgery
Smoking
Pregnancy, lactation, menopause

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Gene expression level of AdipoR1& R2. Timepoint: Before the intervention and two months after the intervention. Method of measurement: Real- time PCR.;Gene expression level of AMPK. Timepoint: Before the intervention and two months after the intervention. Method of measurement: Real- time PCR.;Gene expression level of UCP 2 & 3. Timepoint: Before the intervention and two months after the intervention. Method of measurement: Real- time PCR.

Secondary Outcome Measures

Name	Time	Method
Serum levels of hsCRP. Timepoint: Before the intervention and two months after the intervention. Method of measurement: ELISA kit.;Atherogenic index of plasma(AIP). Timepoint: Before the intervention and two months after the intervention. Method of measurement: based on formula: AIP=log??triglycerides /high density lipoprotein?.