Comparative Evaluation of Microbial Reduction in One-Visit & Two-Visit Endodontic Revisionism: A Randomised Clinical Trial
试验速览
- 阶段
- 2/3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- Microbial Load Reduction using PCR
研究概览
简要总结
One of the main goals of root canal therapy is to eliminate the infectious process by reducing the microbial content to levels compatible with the healing of periapical tissues. However, some microorganisms originally present in necrotic tissues may survive chemomechanical procedures or may be located in missed canals or uninstrumented areas of the root canal system. Persistent bacteria can either induce new inflammation in the periapical region or contribute to the perpetuation of the infectious process even after root canal filling. Nonsurgical root canal retreatment is usually the first treatment option to eliminate infection in root-filled teeth. In these cases, after removal of the filling material, root canal disinfection can be achieved by chemomechanical preparation immediately followed by obturation (1-visit treatment) or supplemented by a previous interappointment intracanal medication (2-visit treatment).
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Single rooted single canal teeth with secondary Endodontic infection.
- •Periapical index score of 1 to 4.
排除标准
- •COMPLICATING SYSTEMIC DISEASE (ASA 3-6) HISTORY OF ANTIBIOTIC USAGE IN THE LAST 3 MONTHS TEETH WITH A HISOTRY OF ROOT CANAL TREATMENT FROM LESS THAN 3 YEARS BACK IN TIME TEETH IN WHICH RUBBER DAM ISOLATION IS NOT FEASIBLE TEETH WITH IATROGENIC ERRORS (PERFORATION, LEDGE, TRANSPORTATON) TEETH WITH INTRARADICULAR POSTS TEETH WITH SINUS TRACT PERIODONTAL POCKETS DEEPER THAN 4mm.
结局指标
主要结局
Microbial Load Reduction using PCR
时间窗: Baseline, 1 week
次要结局
- Post Operative Pain Measurement using Heft Parker Scale(Pre operative, 24 hours, 48 hours, 72 hours, 7 days)