High-frequency oscillations in high-density scalp electroencephalography. Can physiologic and pathologic high-frequency oscillations be distinguished in the high-density scalp electroencephalography using functional paradigms?

• Conditions: G40.0; G40.1; G40.2; Localization-related (focal)(partial) idiopathic epilepsy and epileptic syndromes with seizures of localized onset; Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures; Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures

• Registration Number: DRKS00013287
• Lead Sponsor: Fachbereich Mathematik, Universität Salzburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-11-24
• Study Completion: 2020-02-24
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

focal epilesy; able to give informed consent

Exclusion Criteria

additional progressive neurological diseases
; psychogenic seizures

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Detectability of high-frequency oscillations (HFOs); Comparison between detectability in high-density scalp EEG recordings with Standard clinical EEG recordings.

Secondary Outcome Measures

Name	Time	Method
Improvement of automatic HFO detection algorithsm. Evaluation of the diagnostic value by comparing high density scalp findings with HFO findings from invasive recordings and their relation to surgical outcome. Comparison between evoked physiologic and pathologic HFOs