临床试验/NCT00891865

NCT00891865已完成不适用

Viral Triggers of Alloimmunity and Autoimmunity in Pediatric Lung Transplantation (CTOTC-03)

National Institute of Allergy and Infectious Diseases (NIAID)6 个研究点分布在 1 个国家目标入组 61 人开始时间: 2009年6月最近更新: 2020年7月2日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: National Institute of Allergy and Infectious Diseases (NIAID)
入组人数: 61
试验地点: 6
主要终点: The earliest time to BOS or OB, retransplantation or death

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to determine whether respiratory viral infections increase the risk of bronchiolitis obliterans syndrome (BOS), obliterative bronchiolitis (OB), death, or retransplantation in children who have received lung transplants.

研究设计

研究类型: Observational
观察模型: Case Only
时间视角: Prospective

入排标准

年龄范围: — 至 21 Years（Child, Adult）
性别: All
接受健康志愿者: 否

入选标准

•Parent or legal guardian willing and able to provide informed consent
•Participant of first single or bilateral heart-lung transplant

排除标准

•Recipient of multi-organ transplant (aside from heart-lung)
•Condition or characteristic which in the opinion of the investigator makes the participant unlikely to complete the study

结局指标

主要结局

The earliest time to BOS or OB, retransplantation or death

时间窗: Within 24 months of transplant

次要结局

Time to each of the following events: BOS or OB, retransplantation or death(Within 24 months of transplant)

研究者

发起方

National Institute of Allergy and Infectious Diseases (NIAID)

申办方类型

Nih

责任方

Sponsor

研究点 (6)

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