Altering cough thresholds in stroke patients with use of ultrasonically distilled water in a sensory stimulation protocol

niversity of Canterbury0 个研究点目标入组 50 人开始时间: 2023年4月28日最近更新: 2023年5月15日

试验速览

暂无简介。

•Participants will be/have:
•- Over the age of 18 years
•- Able to give informed consent
•- A diagnosed stroke
•- Intact volitional cough (indicating that motor innervation of the cough response is intact)
•- An absent cough response to a 0.4 mol/L concentration of citric acid (completed in Session 1 after giving consent)
•- Spirometry results that do not demonstrate an obstructive pattern (a lung function ratio that is below the lower limit of the normal range – (completed in Session 1 after giving consent)

•Participants will not be/have:
•- A communication or cognitive impairment
•- A diagnosed progressive neurological disease (eg Multiple Sclerosis, Motor Neurone Disease, Parkinson’s Disease)
•- A history of cancer of the head, neck or lungs
•- Any history of respiratory conditions including COPD and asthma (or any prior use of an inhaler)
•- A current smoker / vaper or have ceased smoking within last 6 months
•- Poorly controlled reflux
•- Currently taking or have taken any opioid pain medications in the last 6 months
•- Currently taking or have taken any ACE inhibitor medications in the last 3 months
•- Currently taking or have taken any antipsychotic medications in the last 6 months
•- A current or recent respiratory tract infection in the last 2 weeks including displaying symptoms of a cold, flu or COVID-19
•- A myocardial infarction in the last 4 weeks
•- Eye surgery in the last 2 weeks
•- Previous bad reaction to any inhaled therapies in the past (e.g. allergic type reaction)

发起方

niversity of Canterbury