investigation of probiotic effects on prophylaxis of pneumonia
Not Applicable
Recruiting
- Conditions
- Ventilator associated pneumonia(VAP).Bacterial pneumonia, not elsewhere classified
- Registration Number
- IRCT20170704034901N2
- Lead Sponsor
- Birjand University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
age over than 18 year
Length of stay in ICU for more than 5 days
Exclusion Criteria
Diarrhea at first visit or 48 hours before admission
immune deficiency
Regular treatment with probiotics before admission
pregnancy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence of ventilator associated pneumonia(VAP). Timepoint: Up to 15 days after starting probiotics, ventilator-associated pneumonia will be examined. Method of measurement: Daily hematologic examination (CBC and neutrophil count), active phase proteins (CRP or proxlotonin or ferritin) and chest X ray, Based on the American College of Chest Physicians clinical criteria, new or sustained infiltration in the CXR with 2 or 3 of the following findings: fever (.38.58C or ,35.08C), leukocytosis (white bloodcells . 10,000/mm3 or ,3,000/mm3), and purulent sputum.
- Secondary Outcome Measures
Name Time Method