to evalaute the effect of local application of tranexamic acid on blood loss during vaginal hysterectomy in adult females
- Conditions
- Health Condition 1: N819- Female genital prolapse, unspecified
- Registration Number
- CTRI/2020/03/024202
- Lead Sponsor
- Dr Sudarshan Dash
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1.patients of age > 18 years undergoing vaginal hysterectomy under spinal anesthesia with or without bilateral salpingooophorectomy (BSO) due to myoma, menorrhagia, metrorrhagia, chronic pelvic pain, and endometrial hyperplasia giving written informed consent.
1.Patients undergoing abdominal or laparoscopic hysterectomy
2.Patients undergoing vaginal hysterectomy under general anesthesia
3.Patients with cardiac, hepatic, renal, or thromboembolic disease
4. Patients with pelvic endometriosis and adnexal mass
5.Patients with endometrial or cervical cancer
6.Patients using Anticoagulants ,NSAIDs, antiplatelets, contraceptive medications, hormone-containing medications, patients on medications for DVT prophylaxis
7. Patients with history of allergy to tranexamic acid.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To estimate intraoperative, postoperative, and total blood loss (ml) in women undergoing vaginal hysterectomy in each groupsTimepoint: day 2 i.e. 24 hours post surgery
- Secondary Outcome Measures
Name Time Method To estimate need for blood transfusion, operative time, and period for hospitalization, hemoglobin concentration 24 h postoperative, and the change in hemoglobin concentration pre- and postoperative in women undergoing vaginal hysterectomy in each group.Timepoint: 24 hours post surgery