Effect of Long-Acting vs. Short-Acting Loop Diuretics and Neurohormonal Agents on Patients' Quality-of-Life Among Patients with Heart Failure
Not Applicable
- Conditions
- Heart failure
- Registration Number
- JPRN-UMIN000045229
- Lead Sponsor
- Keio University School of Medicine, Department of Cardiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 240
Inclusion Criteria
Not provided
Exclusion Criteria
1) Symptomatic hypotension and/or a systolic blood pressure < 100 mmHg at screening 2) Serum potassium greater than or equal to5.4 mEq/L at screening 3) eGFR < 30 ml/min/1.73m or end-stage renal disease requiring renal replacement therapy at the time of screening 4) Pregnant or nursing women, or history of hypersensitivity or allergy to any of the study drugs, drugs of similar chemical classes, as well as known or suspected contraindications to the study drugs. 5) Inability or unwillingness to comply with the study requirements 6) Patients who are unable to obtain written consent or require a substitute.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The mean changes in Kansas City Cardiomyopathy Questionnaire overall summary (KCCQ-OS) score from the start of the intervention to 6 months.
- Secondary Outcome Measures
Name Time Method