Post-Operative Pain Scores and Analgesic Requirements After Elective Inguinal Herniorrhaphy

Phase 2

Terminated

• Conditions: Hernia, Inguinal; Analgesia; Pain
• Interventions: Other: placebo; Drug: Gabapentin

• Registration Number: NCT00735124
• Lead Sponsor: University of Oklahoma

Brief Summary

The study will investigate the effects of single dose pre-operative oral dose of gabapentin (1200) on post -operative pain scores and oral analgesic requirements.

Detailed Description

The study will benefit patients in reducing post-operative pain scores as well as reduction in oral analgesic consumption. Gabapentin has been shown to reduce post operative pain pain scores in breast surgery, hysterectomy , spinal surgery, orthopedic and thyroid surgery

Study Timeline

• Study First Submitted: 2008-08-13
• Study First Submitted QC: 2008-08-13
• Study First Posted: 2008-08-14
• Study Start: 2008-11-06
• Primary Completion: 2009-09
• Study Completion: 2009-09
• Status Verified: 2017-04
• Last Update Submitted: 2017-04-26
• Last Update Posted: 2017-04-28

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 5

Inclusion Criteria

• Subjects having elective surgery with open unilateral Inguinal herniorraphy

Exclusion Criteria

• Non elective surgery
• Patients currently on gabapentin therapy
• Patient hypersensitive to gabapentin surgery
• History of alcohol or drug abuse
• Patients who are pregnant or who are nursing

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo	placebo	Placebo arm for blinding the medication
Single pre-op dose of Gabapentine	Gabapentin	Active treatment with the study drug

Primary Outcome Measures

Name	Time	Method
Post operative pain is reduced when single pre-operative oral dose of Gabapentine is given to the patient before the Inguinal Herniorrhaphy	1yrs	Post operative pain is reduced when single pre-operative oral dose of

Secondary Outcome Measures

Name	Time	Method
The post operative analgesia requirement is also reduced	1yrs	The post operative analgesia requirement is also reduced

Trial Locations

Locations (1)

OUHSC; 🇺🇸 Oklahoma City, Oklahoma, United States