CASPER study
- Conditions
- Pregnancy and Childbirth
- Registration Number
- PACTR202108825067735
- Lead Sponsor
- Preeclampsia Research Laboratories PEARLS Heart Research Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 296
1All urban health centres providing maternal health services in Blantyre
2All Pregnant women screened and identified to be at risk of preeclampsia/ eclampsia such as those with:
Hypertensive disease during previous pregnancy
Chronic kidney disease
Type 1&2 diabetes
Chronic hypertension
Auto immune disease such as systematic lupus erythematosus or antiphospholipid syndrome
previous history of preeclampsia/eclampsia,
previous an explained abruption
advanced maternal/extreme of age, teenagers
3. Those with family history of eclampsia/preeclampsia, twin pregnancy, chronic hypertension, diabetes )
4. They should be between 11 to 16 weeks gestation
1.All women with increased risk of bleeding due to coagulation disorders or placenta previa
2.Women who are allergic to aspirin or calcium
3.Women who are planning to deliver at another health facility
4.All women who did not consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method preeclampsia and or eclampsia
- Secondary Outcome Measures
Name Time Method Maternal mortality, placenta abruptio, admission to ICU, stroke, post partum haemorrhage, timing of delivery, gestational age at delivery, HELLP syndrome, near miss event, birth weight, admission in nursery ICU, intra uterine death, fresh still birth, small for gestational age or neonatal respiratory support.<br><br>