Prescription Pattern and Adverse Events of Postoperative Antithrombotic Regimes for Free Flap Surgery in Head and Neck Cancer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 540
- 试验地点
- 1
- 主要终点
- Number of participants with flap failure
研究概览
简要总结
This is a cohort study collecting patients with head and neck cancer who underwent free flap surgery at a single medical center between January 2019 and January 2022.
详细描述
Patient information are collected from the electronic medical records retrospectively:
Head and Neck cancer diagnosis: The International Classification of Diseases, Tenth Revision (ICD-10), which included C00-C14, C31, C32, C73, C75.0, C75.4 and C41.1.
The cancer stage, alcohol use, betel nut, and smoking, and baseline comorbidities.
Surgical characteristics including flap history, ablation time, reconstruction time, donor sites, recipient sites, neck dissection, flap size, anastomosis, artery types, vein types, intraoperative sealants used, and intravenous calcium channel blocker nicardipine to control hypertension after surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age greater and equal to 20 years old
- •Underwent free flap surgery
- •Had head and neck cancer
排除标准
- •HIV positive
- •Pregnant, breast feeing women
- •Missing surgical charts
结局指标
主要结局
Number of participants with flap failure
时间窗: 30 days post-operation
Flap necrosis with a need for a new flap or other surgical procedures.
次要结局
- Number of participants with thrombosis(30 days post-operation)
- Number of participants with hematoma(30 days post-operation)
研究者
Ying-Chi Lin
Director, Master Degree Program in Toxicology
Kaohsiung Medical University