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Randomised controlled trial of soluble plantain fibre for maintenance of health during periods of remission in Crohn's disease v2 - Plantain NSP in Crohn's disease

Phase 1
Conditions
Crohn's Disease
MedDRA version: 13.1 Level: PT Classification code 10011401 Term: Crohn's disease System Organ Class: 10017947 - Gastrointestinal disorders
Registration Number
EUCTR2006-005526-23-GB
Lead Sponsor
Provexis Plc
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Not specified
Target Recruitment
76
Inclusion Criteria

(i) Patients with Crohn’s disease as diagnosed by conventional clinical, radiological and histological criteria. (ii) Crohn’s disease involving small bowel, colon or both. (iii) Crohn’s disease that is in remission: Crohn’s Disease Activity Index (CDAI) < 150 (iv) Patients who have had a relapse of disease within the previous 12 months (Harvey Bradshaw Index modified for retrospective use).
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

(i) Patients under 18 or unable to give informed consent. (ii) Patients who have had surgery for Crohn’s disease within the previous 12 months. (iii) Any change to medication for Crohn’s disease within the previous 3 months. (iv) Patients receiving corticosteroids or infliximab or anti-TNFs within the previous 3 months. (v) CDAI >150 (viii) Patients currently receiving enteral nutrition as part of their treatment for Crohn’s disease. (viii) Participation in other trials in the last 3 months.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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