Acetylsalicylic acid as an adjuvant therapy for schizophrenia.
Completed
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
1. Schizophrenia
2. Schizo-affective disorder
3. Schizofreniform disorder according to DSM-IV (for max 10 years)
4. Age 18 - 55 years
5. Stabile, min. 60 on PANSS, min 2x a score of min 4 on PANSS.
Exclusion Criteria
1. No contraindication for acetylsalicylic acid
2. No hypersensitivity to acetylsalicylic acid or pantoprazole
3. No significant somatic illness
4. No chronic use of a nonsteroidal anti-inflammatory drug (NSAID)
5. No use of corticosteroids
5. Not pregnant
6. No drugs dependency
7. Informed consent obtained.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 3-month change in positive and negative symptoms on the total PANSS score.
- Secondary Outcome Measures
Name Time Method 3-month change in the PANSS subscales, cognitive symptoms, immunological parameters (g-interferon, IL-4, IL-6 and IL-12).