Effectiveness of Pippalyadi Avapida Nasya followed by Anutaila Pratimarsha Nasya in Pratishyaya (Chronic Rhinosinusitis).

Phase 3

Conditions: Health Condition 1: J310- Chronic rhinitis

Registration Number: CTRI/2024/01/061049

Lead Sponsor: orth Eastern Institute of Ayurveda and Homoeopathy Ministry of Ayush Govt

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1.Patient who are willing to participate in the study and ready to give a written informed consent.

2.Subjects of either sex in the age group of 18 to 60 years.

3.Patients who are having the clinical signs and symptoms of Pratishyaya.

4.Patients fulfilling the criteria of chronic rhinosinusitis as per American Academy of Otolaryngology—Head and Neck Surgery (2015).

Exclusion Criteria

1.Patient with migraine, tension type of headache, cluster headache, glaucoma or any other type of headache, except sinusitis.

2.Patients with space occupying lesion of brain.

3.Patients with nasal polyp, deviated nasal septum or any benign or malignant growth of nose and paranasal sinuses.

4.Known patient of epilepsy, mental disorder, malignancy, serious acute organic disease, or any serious comorbidity that will make it impossible to participate in the trial interventions.

5.Pregnant or lactating women.

6.Patients with contraindication of nasya karma.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Classical parameters of Pratishyaya <br/ ><br>2. Sino-Nasal Outcome Test - 22 (SNOT-22) questionnaire score <br/ ><br>3. Sino-Nasal Outcome Test - 20 (SNOT-20) questionnaire score <br/ ><br>4. Sinus Control Test (SCT) <br/ ><br>5.Haziness over the PNS (Maxillary sinuses) in X-Ray PNS water’s view <br/ ><br>6.Haziness over the frontal sinuses in X-Ray Skull Caldwell view <br/ ><br>7.Erythrocyte Sedimentation Rate (ESR) <br/ ><br>8.C-Reactive Protein (CRP) <br/ ><br>Timepoint: Base line <br/ ><br>15th day <br/ ><br>30th day

Secondary Outcome Measures