Effect of vitamin C and omega-3 on the incidence of AF after surgery, length of stay in the ICU, and fatigue in patients with open heart surgery
- Conditions
- Atrial fibrillation.Atrial fibrillation and flutter
- Registration Number
- IRCT2015091924080N1
- Lead Sponsor
- Vice chancellor for research Lorestan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 160
Age between 30 and 90 years; patients candidate by physicians for open heart surgery (coronary artery bypass graft, with or without valve surgery) ; having sinus rhythm in ECG before surgery; provide informed written consent; Do not use vitamin supplements containing antioxidants or omega-3 supplements and don't use of fish oil in the last three months ; Now is not pregnant; Known allergy or intolerance fish oil and vitamin C ; comorbidities such as chronic rheumatoid arthritis, malignancy, chronic renal failure, severe liver failure (serum creatinine> 2.0 mg / dL), and recent infection
Exclusion criteria:
Sensitivity to omega-3 and vitamin C (during studies) or severe gastrointestinal side effects (diarrhea) ; Currently is pregnant ; for a heart transplant or ventricular assist devices are planned ; Now reluctant to provide information and is not satisfied ; use of anti-arrhythmic drugs class 1 and 3 ; congenital heart Diseases ; CPR during or after surgery
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence of atrial fibrillation. Timepoint: While intervention. Method of measurement: The number of cases and counting.;Length of stay in the icu, post icu, and the length of stay in hospital. Timepoint: While intervention. Method of measurement: In terms of time.;Fatigue. Timepoint: Before and after the intervention. Method of measurement: Tools mfi-20.
- Secondary Outcome Measures
Name Time Method Metoral drug. Timepoint: preintervention. Method of measurement: Observation.;Ejection fraction. Timepoint: preintervention. Method of measurement: Observation.