NCT02207192已完成不适用
Effect of Weight Loss on Postural Changes in Pulmonary Function : a Longitudinal Study in Morbidly Obese to Obese Subjects Following Gastroplasty
Association pour la Formation du Personnel à la Medecine d'Urgence1 个研究点 分布在 1 个国家目标入组 12 人开始时间: 2005年8月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- functional residual capacity
研究概览
简要总结
Postural changes are known to affect normal lung volumes. A reduction in sitting to supine functional residual capacity (FRC) is well-described in non-obese subjects adopting a supine position. However, postural changes in lung volumes in the obese require further exploration. We aimed to longitudinally address the effects of weight loss on postural changes in lung volumes and pulmonary function, in obesity. We tested the hypothesis that supine reduction in FRC would be absent in morbid obesity and recovered upon weight loss.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 60 Years(Child, Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •subjects scheduled for bariatric surgery (BMI over or equal to 40 kg/m2)
排除标准
- •Subjects with respiratory and cardiac history (asthma, COPD, heart failure) were excluded.
结局指标
主要结局
functional residual capacity
时间窗: baseline and one year after bariatric surgery
次要结局
- lung volumes and flows(at baseline and after bariatric surgery)
研究者
研究点 (1)
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