antiretroviral therapy regimen intensified with maraviroc during early HIV-1 infectio
- Conditions
- HIV-1 infection
- Registration Number
- JPRN-UMIN000017975
- Lead Sponsor
- ational Hospital Organization Osaka National Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Not provided
1) coronary diseases: unstable angina or history of acute myocardial infarction within 6 months before entry 2) Viral hepatitis (HBV,HCV) 3) Any verified Grade 4 laboratory abnormality (excluding abnormal lipid metabolism) 4)Alanine aminotransferase (ALT) greater than 5 times the upper limit of normal 5) Subject has creatinine clearance of less than 50 mL/min via Cockroft-Gault method 6)Any evidence of primary viral resistance based on the presence of any major resistance-associated mutation [IAS-USA, 2014] in the Screening result or, if known, any historical resistance test results 7) Women who are pregnant or sexually active without effective contraception 8) Subjects whom investigators consider to be inappropriate to enroll in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of patients achieving plasma viral load less than 50 copies/mL at week 48
- Secondary Outcome Measures
Name Time Method