Skin Glue Versus Suture for Securing Radial Arterial Lines

Not Applicable

Completed

• Conditions: Arterial Catheters; Catheter Related Complication

• Registration Number: NCT06589284
• Lead Sponsor: CHRISTUS Health

Brief Summary

Prior investigators have evaluated the use of 2-octyl cyanoacrylate (glue) as a method to secure a variety of venous catheters including central/peripheral lines. There is a paucity of research evaluating the use of glue for arterial catheters. The investigators conducted a pilot study to test the null hypothesis that there would be no difference in failure rates between radial arterial lines (r-a-line) secured with glue vs. suture.

Detailed Description

This was a prospective, randomized, controlled, trial for which the investigators enrolled a convenience sample of consenting, non-pregnant, adult patients who received an r-a-line in the ICU or ED at a community-based, teaching hospital. After randomization, lines were secured with either silk 0-0 suture or 2-octyl cyanoacrylate and, then, covered by chlorhexidine gluconate dressing. Patients were followed for duration of line placement and for the occurrence of premature line failure. Categorical data were analyzed by chi-square; continuous data by t-tests.

Study Timeline

• Study Start: 2023-06-15
• Primary Completion: 2024-06-14
• Study Completion: 2024-06-14
• Status Verified: 2024-07
• Study First Submitted: 2024-07-18
• Study First Submitted QC: 2024-09-05
• Last Update Submitted: 2024-09-05
• Study First Posted: 2024-09-10
• Last Update Posted: 2024-09-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

1. Be at least 18 years of age
2. Require invasive blood pressure monitoring via radial arterial catheter

Exclusion Criteria

1. Under 18 years of age
2. Pregnant

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Length of time which the catheter remained in place	12 months	Primary outcomes measured were length of time of which the catheter remained in place and causes of premature failure, if it occurred.
Cause of premature failure (if occurred)	12 months	Primary outcomes measured were length of time of which the catheter remained in place and causes of premature failure, if it occurred.

Secondary Outcome Measures

Name	Time	Method
Evaluation of patient demographics for line failure	12 months	Secondary outcomes included an evaluation of patient and line placement demographics for line failure between both suture and skin glue groups.
Evaluation of line placement for line failure	12 months	Secondary outcomes included an evaluation of patient and line placement demographics for line failure between both suture and skin glue groups.

Trial Locations

Locations (1)

CHRISTUS Spohn Hospital Corpus Christi - Shoreline; 🇺🇸 Corpus Christi, Texas, United States