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Clinical Trials/NCT05027412
NCT05027412
Unknown
Not Applicable

Transurethral En Bloc Resection With Collins Loop vs Conventional Transurethral Resection for the Treatment of Urothelial Bladder Carcinoma

Hospital Universitario de Fuenlabrada1 site in 1 country80 target enrollmentApril 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Bladder Cancer
Sponsor
Hospital Universitario de Fuenlabrada
Enrollment
80
Locations
1
Primary Endpoint
presence of detrusor muscle in the resected sample
Last Updated
4 years ago

Overview

Brief Summary

This is a prospective, randomized, randomized and single-blind study in patients diagnosed with primary bladder CV. Patients diagnosed by cystoscopy of a bladder tumor and with indication for endoscopic surgical treatment, who meet the inclusion criteria, and who sign the Informed Consent (IC), will be randomized.

Detailed Description

The main objective of the study is to assess the quality of the resection, defined as the presence of detrusor muscle in the resected tissue. The secondary objetives are: * Compare the surgical time, hospital stay, urinary catheterization time and incidence of complications. * Compare tumor recurrence after one year of follow up. * Determine the number of re-TURB as a consequence of the absence of muscle layer in the sample or artifacts (Tx) * Establish the incidence of conversions as a consequence of difficulties in the technique or intraoperative bleeding. * Compare the degree of satisfaction of the surgeon

Registry
clinicaltrials.gov
Start Date
April 1, 2021
End Date
June 2023
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Berta Nasarre

Attending Physician

Hospital Universitario de Fuenlabrada

Eligibility Criteria

Inclusion Criteria

  • \>18 years old.
  • Polypoid / sessile primary tumor.
  • \< 3 tumors
  • Tumor size 10 - 30 mm.

Exclusion Criteria

  • \> 4 tumors
  • Size of the largest tumor \<1 cm and\> 4 cm.
  • Tumor located in the bladder dome.
  • No visualization of the ureteral meatus.
  • Flat or in situ tumor.
  • Non-urothelial tumors.
  • Clotting disorder or treatment with oral anticoagulants.

Outcomes

Primary Outcomes

presence of detrusor muscle in the resected sample

Time Frame: 1 year of follow up

yes/no

Study Sites (1)

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