Effect of High- Definition Transcranial Direct Current Stimulation on Cognitive Deficits in Schizophrenia
Not Applicable
- Conditions
- Health Condition 1: null- Schizophrenia
- Registration Number
- CTRI/2018/04/013413
- Lead Sponsor
- Dr Sowmya S
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Diagnosis of Schizophrenia and related disorders as per DSM criteria(Diagnostic and Statistical Manual for Mental Disorders, American Psychiatric Association), Right-handed, Lack of clinically significant positive symptoms as per established criteria and patient being on stable medications, Minimum education upto 8th standard, having significant cognitive deficits according to predefined criteria, Written informed consent obtained.
Exclusion Criteria
Any contraindication to tDCS procedure (for example, metal in the head, implanted brain medical devices, local lesion or injury in the scalp/head), Co-morbid substance dependence (except tobacco and caffeine), Co-morbid neurological disease, Left/Mixed Handedness.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Severity of Working memory deficits. <br/ ><br>2. Change in the neural correlates involved in Working memory deficits(Using brain imaging techniques like, structural MRI,resting fMRI, task based fMRI)Timepoint: Twice. First time (Day 1), before the treatment <br/ ><br>with HD-tDCS is given. And second time on the last day(day 5), after the completion of 10 session of HD-tDCS treatment.
- Secondary Outcome Measures
Name Time Method Change in the neural correlates involved in Working memory deficits(Using brain imaging techniques like, structural MRI,resting fMRI, task based fMRI)Timepoint: Twice. First time (Day 1), before the treatment <br/ ><br>with HD-tDCS is given. And second time on the last day(day 5), after the completion of 10 session of HD-tDCS treatment.