Pomegranate Juice Effect on Oxidative Stress in Infertile Women During IVF Treatment

Not Applicable

• Conditions: Endometriosis; Male Factor Infertility; PCOS; Advised Maternal Age
• Interventions: Other: Pomegranate juice; Other: Apple juice

• Registration Number: NCT03978013
• Lead Sponsor: Rambam Health Care Campus

Brief Summary

tTe investigators estimate pomegranate supplementation effect on oxidative stress in infertile women with PCOS, endometriosis and advanced maternal age during IVF treatment. The primary aim is to compare the obtained oxidative stress markers in follicular fluid with pomegranate supplementation vs control.

Detailed Description

Not available

Study Timeline

• Status Verified: 2019-06
• Study First Submitted: 2019-06-02
• Study First Submitted QC: 2019-06-05
• Last Update Submitted: 2019-06-05
• Study First Posted: 2019-06-06
• Last Update Posted: 2019-06-06
• Study Start: 2019-09-01
• Primary Completion: 2020-12-01
• Study Completion: 2021-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

• Patients undergo IVF treatment with diagnosis of PCOS/Endometriosis/MF or AMA

Exclusion Criteria

• Patients who do not meet the inclusion criteria, as above

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Pomegranate	Pomegranate juice	-
Apple	Apple juice	-

Primary Outcome Measures

Name	Time	Method
Cytokines levels in follicle fluid	2 weeks	Cytokines (pg/mL) will be mesured by elisa.