Safety and efficacy of cord blood transplantation for hematologic malignancies (OCU 9-2)
- Conditions
- Acute myeloid leukemia AML with multilineage dysplasia Myelodysplastic syndrome Acute lymphoblastic leukemia Chronic myeloid leukemia Adult T cell leukemia/lymphoma Malignant lymphoma
- Registration Number
- JPRN-UMIN000002214
- Lead Sponsor
- Hematology, Osaka City University, Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Not provided
1. Dysfunction of major organ which meets any of the following criteria. a. T-Bil > 2.0mg/dl b. Cre > 2.0mg/dl c. EF >30% d. %VC <30%, FEV1.0% <40% or SaO2 < 50mmHg on room air (SpO2 <90%) e. AST: beyond 3 times of UNL 2. Active infection 3. Poorly controlled diabetes mellitus despite the use of insulin 4. Poorly controlled hypertention 5. Severe complications including heart failure, coronary failure, myocardial infarction within the last 3 months, liver cirrhosis and interstitial pneumonia 6. Pregnant, nursing of possible fertile woman 7. Severe mental disorder who is unlikely to be able to participate in the study 8. A history of hypersensitivity or allergy to any drugs in conditioning regimen of this transplantation 9. HIV antibody positivity 10. No indication for this study judged by physician in charge
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method