Stem Cells in Umbilical Blood Infusion for Cerebral Palsy

Not Applicable

Completed

• Conditions: Cerebral palsy; Neurological - Other neurological disorders

• Registration Number: ACTRN12616000403437
• Lead Sponsor: Murdoch Childrens Research Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-03-30
• Study Completion: 2020-04-30
• Last Update Posted: 16 February 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

1.Diagnosis of any type of CP
2.CP of any severity
3.A record of sibling CBU in storage at a TGA accredited private cord blood bank
4.Ability to travel to one of the trial centres
5.Ability to participate in assessments
6.Informed consent by parents

Exclusion Criteria

1.presence of progressive neurological disease
2.known genetic disorder
3.known brain dysplasia
4.immune system disorder or immune deficiency syndrome
5.infectious disease markers showing up on the virology screen
6.evidence of cord blood unit contamination, or fewer than 10^7 cells/kg body mass
7.ventilator support
8.ill health, or if the participant’s medical condition does not allow safe travel
9.previous cell therapy
10.Botulinum toxin A within 3 months before or after infusion
11.Surgery within 3 months before or after infusion
12.Cannot obtain parental consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified