The use of microscopic optical coherence tomography in patients with Fuchs corneal endothelial dystrophy

• Conditions: H18.5; Hereditary corneal dystrophies

• Registration Number: DRKS00018848
• Lead Sponsor: niversitätsklinikum Köln

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-12-11
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting withdrawn before recruiting started
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients
- male, female, older than 18 years, able to give written consent
- availaben written consent
- diagnosed with Fuches endothelial dystrophy
- culture time maximum 50 days, preferably less than 35 days
- consent of the donor or next relative for usage in this study
- not eligible for transplantation

Exclusion Criteria

Patient:
- known infectious diseases
- other ophthalmological diseases than FED or Cataracta
- no consenct for scientific studies
- culture lenght > 50 days

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To obtain detailed information about ultrastructural changes in cornea explants of healthy individuals and FED-patients.<br>The corneas of FED-patients are obtained when these patients undergo surgical treatment (Descemet membrane endothelial keratoplasty). The corneas of healthy individuals are obtained from the Gewebebank Mecklenburg-Vorpommern. These are corneas stored for scientific purpose.