STRAP – STudy to Reduce Antibiotic prescription in childhood Pneumonia

Completed

• Conditions: children; pneumonia; prediction; antibiotic use; antibiotica; pneumonie; kinderen

• Registration Number: NL-OMON28856
• Lead Sponsor: Erasmus MC - Sophia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 1100

Inclusion Criteria

children aged 1 month – 5 years with fever (parent reported and/or measured during physical examination T >38°C) with signs suspected of community acquired pneumonia (CAP)

Exclusion Criteria

-febrile children with antibiotic treatment during the week prior to the ED visit

-children with comorbidity, i.e. hemodynamic relevant cardiac disease, pulmonary, neurologic disease or (primary of secondary) immunodeficiency

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of (narrow-spectrum) antibiotic prescriptions and its percentage within the total included population (benefit); Strategy failures (children with complications of CAP within 7 days) (safety).

Secondary Outcome Measures

Name	Time	Method
-Compliance to the advice of the feverkidstool; percentage and number of narrow versus broad-spectrum antibiotic prescriptions; Duration and dosages of antibiotic prescriptions<br /><br>-Safety: Number of complications of pneumonia, association of isolated pathogens with complicated CAP course