Study of Hypothalamic Metabolism in Spontaneous Cluster Headache Attacks
Not Applicable
Terminated
- Conditions
- Cluster Headache
- Registration Number
- NCT00458770
- Lead Sponsor
- Assistance Publique Hopitaux De Marseille
- Brief Summary
Cluster headache is characterized by unilateral excruciating head pain and autonomic dysfunction. Hypothalamic overactivity was observed in nitrate-induced cluster-headache and in only one case of spontaneous cluster headache 'Sprenger et al, 2004). This prompted the application of hypothalamic deep brain stimulation. The aim of this data is to precise the localisation of the hypothalamic activation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 1
Inclusion Criteria
- cluster headache in crisis
- no serious illnesses in progress as cancer, autoimmune disease, liver disease
- patient without chronic psychiatric disease excluding moderate and reactional depression
- no demential disease
- no anxious or depressive disease
- no contraindication to PET scan (pregnancy and breast-feeding)
- social security cover
- written informed consent
Exclusion Criteria
- No effective contraception taken
- unable to realize a decubitus of 15 minutes long
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method To confirm the existence of a hypothalamic promoter at the origin of Spontaneous Cluster Headache Attacks 2 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Pôle de Neurosciences Cliniques CHU Timone
🇫🇷Marseille, France