se of insulin sensitisers to revert metabolic syndrome

Completed

• Conditions: ow birthweight, subsequent catchup and metabolic syndrome; Pregnancy and Childbirth; Disorders related to short gestation and low birth weight, not elsewhere classified

• Registration Number: ISRCTN58810841
• Lead Sponsor: Hospital Sant Joan de Deu (Spain)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-02-27
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

1. Prepubertal children, both males and females
2. Birthweight less or equal to -2.0 SDS for gestational age, at term (37-42 week)
3. Postnatal catchup (weight and height >p25 in the first 2 years of life)
4. Body Mass Index (BMI) >p75 and 5. Increased visceral fat (MR): >p75
6. Insulin-like growth factor-I (IGF-I) levels >p75
7. Fasting insulin >p75

Exclusion Criteria

1. Syndromatic, chromosomal, or infectious origin of Small for Gestational Age (SGA)
2. Gestational diabetes
3. Hypothyroidism
4. Systemic disease
5. Precocious pubarche
6. Precocious puberty

Study & Design

• Study Type: Interventional
• Study Design: Not specified