Effects of erythropoietin (EPO) on cognitive side-effects of electroconvulsive therapy (ECT) (EPO-T)

Region Hovedstadens psykiatriske hospital0 个研究点目标入组 52 人开始时间: 2016年6月28日最近更新: 2020年6月2日

试验速览

暂无简介。

•We will recruit patients with unipolar or bipolar depression who are
•scheduled for ECT treatment at Psychiatric Centre Copenhagen and
•Psychiatric Centre Frederiksberg (and other centers in the Capitol Region
•if necessary). Patients will be screened with Mini Mental Neuropsychiatric Interview (M.I.N.I.) to confirm ICD-10 diagnosis.
•Eligible patients are between 18-70 years old and have a diagnosis of
•major depression (MDD) unipolar or bipolar (BD) with current moderate
•to severe depressive symptoms. They should have a Hamilton
•Depression Rating Scale 17-items (HDRS-17) score =17, have Danish as
•their native language and be able to give informed consent.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 42
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 10

•Exclusion criteria are: treatment under involuntary measures, previous ECT within the last three months, other neuropsychiatric conditions,
•alcohol or substance misuse disorder. To ensure safety of EPO treatment, patients are also excluded if they have a significant medical
•condition (incl. diabetes, renal failure, epilepsy, hypertension,
•malignancies or thromboses), pregnancy, contraceptive
•medication or a family history of thromboses or seizures.

发起方

Region Hovedstadens psykiatriske hospital