Autonomic Dysfunction in Patients with Migraine: Cardiovascular and Neurophysiology Assessment

Active, not recruiting

• Conditions: Migraine Headache

• Registration Number: NCT06798259
• Lead Sponsor: Beni-Suef University

Brief Summary

Autonomic dysfunction in patients with migraine: cardiovascular and neurophysiology assessment.

Detailed Description

assessment if Autonomic dysfunction in patients with migraine by using cardiovascular assessment by HOTLER MONITORING and table tilt test and neurophysiology assessment by sympathetic skin response

Study Timeline

• Status Verified: 2025-01
• Study Start: 2025-01-07
• Study First Submitted: 2025-01-07
• Study First Submitted QC: 2025-01-22
• Last Update Submitted: 2025-01-22
• Study First Posted: 2025-01-29
• Last Update Posted: 2025-01-29
• Primary Completion: 2025-07-30
• Study Completion: 2025-09-30

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 116

Inclusion Criteria

• 1.fulfilling ICHD-3 criteria for migraine 2. migraine for at least 3 months.

Exclusion Criteria

brain imaging showing structural brain lesions. .medications that could impact autonomic function such as tricyclic antidepressants, anticholinergics, or opioids.

• Patients with concomitant medical illness causing autonomic dysfunction such as: diabetes, cardiovascular, demyelinating or degenerative neurological disorders.
• Contraindications for performing the tilt test
• Pregnant patients.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Autonomic dysfunction in patients with migraine	baseline	assessment of autonomic dysfunction using Composite autonomic system Score 31

Secondary Outcome Measures

Name	Time	Method
Cardiovascular assessment	24 hours	Cardiovascular is done using Holter monitoring and table tilt est

Trial Locations

Locations (1)

Benisuef university hospital; 🇪🇬 Benisuef, Egypt