Comparison of efficacy of erector spinae plane block with paravertebral block for postoperative pain management in patients undergoing breast cancer surgeries
Phase 4
- Conditions
- Health Condition 1: C509- Malignant neoplasm of breast of unspecified site
- Registration Number
- CTRI/2020/06/025611
- Lead Sponsor
- Safdarjung hospital and Vardhman Mahavir Medical College New Delhi India
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
This study will be conducted in adult female patients of age 18 - 60 years weighing > 50 kgs, fulfilling criteria of American Society of Anaesthesiology (ASA) physical status i and ii undergoing elective modified radical mastectomy (MRM) for breast cancer under general anaesthesia with controlled ventilation.
Exclusion Criteria
1. coagulation disorder, local infection, allergy to study drugs
2. anatomic deformity of spine or chest wall
3. pregnant patient
4.morbid obesity
5. liver or renalinsufficiency, respiratory/ cardiac/ psychiatric disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of Analgesia- time from administration of the block till time of administration of first rescue analgesia to the patient will be noted (primary objective).Timepoint: Preoperative vitals to be noted at time 0. <br/ ><br>Intraoperative vitals to be noted at before block, 10, 20, 30, 40, 50, 60, 90, 120, 150, 180 mins after the block. <br/ ><br>postoperative: <br/ ><br>1. VAS assessment at 0,1,2,4,6.,12,24 hours <br/ ><br>2. PONV score assessed at 0,6,12,24 hours.
- Secondary Outcome Measures
Name Time Method 1) Visual Analogue Scale (VAS) <br/ ><br>2) Total intraoperative requirement of fentanyl <br/ ><br>3) Total amount of tramadol required in first 24 hours postoperatively <br/ ><br>4) Postoperative nausea and vomiting <br/ ><br>5) Adverse effects if any <br/ ><br>6) Patient satisfaction using numeric rating scale (nrs) <br/ ><br>7) Number of dermatomal segments blocked postoperatively <br/ ><br>Timepoint: VAS at 0,1,2,4,6,12,24 hours <br/ ><br>Postoperative nausea and vomiting at 0,6,12,24 hours <br/ ><br>