The effect of ondansetron on the prevention of hypotension after spinal anesthesia
Phase 3
Recruiting
- Conditions
- Hypotention induced by spinal anesthesia.
- Registration Number
- IRCT20201006048947N1
- Lead Sponsor
- Jahrom University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Candidates for orthopedic surgery by spinal anesthesia at Peymanieh Hospital in Jahrom
Satisfaction of the person to participate in the study
age between 18 to 65 years
Exclusion Criteria
Patients with hypertension
weight more than 100 kg
motion sickness
cardiac and liver desease and migrain
allery to ondansetron drugs
using any drugs that change blood pressure or hear rate and any drugs that effects by serotonin receptor
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of people with hypotension. Timepoint: Blood pressure measurement during the first 10 minutes, every 3 minutes and then every 5 minutes until the end of 30 minutes of spinal anesthesia. Method of measurement: Measurement with heart monitoring device.
- Secondary Outcome Measures
Name Time Method Percentage of people with decreased heart rate. Timepoint: during the first 10 minutes, every 3 minutes and then every 5 minutes until the end of 30 minutes of spinal anesthesia. Method of measurement: Measuring heart rate with a heart rate monitor.;Percentage of people with pruritus after spinal anesthesia. Timepoint: Every 10 minutes after spinal anesthesia. Method of measurement: by asking the patient.;Percentage of people with nausea after spinal anesthesia. Timepoint: Every 10 minutes after spinal anesthesia. Method of measurement: by asking the patient.