Prefrontal Cortex and Abstract Thinking

Completed

• Conditions: Abstract Thinking; Concept Formation
• Interventions: Behavioral: Neuropsychological examination; Other: MRI

• Registration Number: NCT01100281
• Lead Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Brief Summary

The capacity of concept formation is not well understood, even if a link is supposed with the functioning of the frontal lobes.

Our aim is to better understand the cognitive mechanisms underlying this function and to try to correlate the performance with atrophy of the frontal lobe in neurodegenerative diseases involving this region (frontotemporal lobar degeneration and progressive supranuclear palsy).

Detailed Description

Not available

Study Timeline

• Study Start: 2010-04
• Study First Submitted: 2010-04-07
• Study First Submitted QC: 2010-04-07
• Study First Posted: 2010-04-08
• Study Completion: 2011-04
• Status Verified: 2011-12
• Last Update Submitted: 2011-12-08
• Last Update Posted: 2011-12-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 69

Inclusion Criteria

• informed consent signed
• MMSE> 20
• No contra indication to MRI

Exclusion Criteria

• MMSE<20

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Alzheimer's disease	MRI	-
PSP (Progressive supranuclear palsy)	Neuropsychological examination	-
PSP (Progressive supranuclear palsy)	MRI	-
FTD (Frontotemporal lobar degenerative)	Neuropsychological examination	-
FTD (Frontotemporal lobar degenerative)	MRI	-
Alzheimer's disease	Neuropsychological examination	-

Trial Locations

Locations (1)

Inserm U 975; 🇫🇷 Paris, France